Skip Navigation LinksHome   |   Reference Center   |   Slides and Reports   |   Summary Slides
  • Print
  • Share

Summary Slides - HCT Trends and Survival Data

Using information from our outcomes database, CIBMTR annually prepares and distributes charts summarizing current uses and outcomes of allogeneic and autologous hematopoietic cell transplantation (HCT) in a set of Summary Slides.

 

Summary Slides

The Summary Slides are an annual report on data submitted to the CIBMTR.  The slides are available in one comprehensive, downloadable set.

Summary Slides 2013 (PowerPoint)

  • Slides 3 to 23 exhibit data on frequency of transplants according to age, donor and transplant type, graft source and disease, and early outcomes such as 100-day mortality by disease and transplant type. All frequencies represent first transplants registered with the CIBMTR during the period, except when stating frequencies in the US. Slides 3,8 and 9 represent estimated frequencies of total number of transplants expected in the US.
  • Slides 24 to 42 include overall survival outcomes according to disease, disease status, donor type, year of transplant and conditioning regimen intensity. Comparisons across survival curves are univariate and do not adjust for all potentially important factors; consequently, results should be interpreted cautiously.

Return to top

To cite Summary Slides

Pasquini MC, Wang Z. Current use and outcome of hematopoietic stem cell transplantation: CIBMTR Summary Slides, 2013. Available at: http://www.cibmtr.org

Return to top

Request Summary Slides


Slides are also available upon request by contacting:

Sandra Korman, MS
CIBMTR
9200 W. Wisconsin ave
Suite C5500
Milwaukee, WI 53226 USA
Telephone: 414-805-0682
Fax: 414-805-0714
E-mail: inforequest@mcw.edu

Return to top

Supplemental information on Summary Slides

 
  • Charts with total transplant numbers are estimates based on data reported to CIBMTR, adjusted according to transplant type. These adjustments come from comparisons with other national and international databases.
  • Acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML) are classified as:
    • early phase (first complete remission [CR1] or first chronic phase [CP1]),
    • intermediate phase (second or subsequent CR or CP or accelerated phase [AP]), or
    • advanced phase (primary induction failure, active disease or blastic phase) disease.
  • Myelodysplastic syndrome (MDS) is divided into:
    • early (refractory anemia [RA] or refractory anemia with ringed sideroblasts [RARS]), and
    • advanced (refractory anemia with excess blasts [RAEB] or chronic myelomonocytic leukemia [CMML]) disease.
  • Lymphoma is classified according to sensitivity to prior chemotherapy (chemosensitive or chemoresistant).
  • The classification of conditioning regimen intensities is based on the agents, doses and schedules used. Several classifications are available, and for this report we used a composite classification. Cases defined as reduced-intensity by the transplant center were classified as reported. Cases without such information and with available data on chemotherapy agents, radiation and doses, were classified according to the CIBMTR operational definition of conditioning regimen intensity:
    • Myeloablative conditioning regimen: regimens with total body irradiation single doses of ≥500 cGy, or fractionated doses totalling ≥800 cGy, busulfan doses of >9mg/kg, or melphalan doses of >150 mg/m2 given either as single agents or in combination with other drugs.
    • Reduced-intensity conditioning regimen: regimens with lower doses of total body irradiation, fractionated radiation therapy, busulfan, and melphalan than those used to define a myeloablative conditioning regimen (above).

Return to top

 ​


View current and planned studies
Last Updated: 6/28/2014 2:29 PM