Question 45: Was specific therapy used to prevent liver toxicity?
Liver toxicities in transplant patients may be related to drugs / treatments, infection, GVHD, iron overload, cirrhosis, or sinusoidal obstructive syndrome (SOS) / veno-occlusive disease (VOD). Agents such as ursodiol may be given as prophylaxis against one or more of these transplant-related liver injuries. Agents given to prevent liver toxicity will generally be started prior to or during the conditioning regimen, and may be continued well after transplant.
Indicate whether the recipient received any therapy intended to prevent liver toxicity during the reporting period, including therapy given during the conditioning regimen. Report only agents given to prevent liver toxicities, not those given to treat a diagnosed liver injury or toxicity. If liver toxicity prophylaxis was given, report Yes. If liver toxicity prophylaxis was not given during the reporting period, report No and go to question 48.
Questions 46 – 47: Specify therapy (check all that apply)
Select the agent(s) given during the reporting period to prevent liver toxicity, including therapy given during the conditioning regimen. Only report agents given to prevent liver toxicities, not those given to treat a diagnosed liver injury or toxicity. If Other therapy is reported, specify agent(s).
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