Drugs may be given during the peri-transplant period to prevent transplant-related complications, such as liver injuries or to facilitate engraftment.

Questions 136 – 144: Drugs

For each agent listed, indicate whether the drug was administered during the peri-transplant period to prevent transplant-related complications or facilitate engraftment, and any additional question(s) for each drug administered.

ALG (Anti-Lymphocyte Globulin), ALS (Anti-Lymphocyte Serum), ATG (Anti-Thymocyte Globulin, ATS (Anti-Thymocyte Serum): Serum or gamma globulin preparations containing polyclonal immunoglobulins directed against lymphocytes. These drugs are usually prepared from animals immunized against human lymphocytes. Report the total dose prescribed in question 137 and the animal source in question 138. If Other is selected, specify the source in question 139.

Alemtuzumab (Campath): Antibody preparations that are infused in the recipient. Report the total dose prescribed to the nearest tenth and specify the units of measurement in question 141.

Defibrotide: Antithrombotic agent used to prevent veno-occlusive disease.

KGF (keratinocyte growth factor): Alternate names: palifermin, Kepivance. KGF acts to stimulate the growth of cells that line the surface of the mouth and intestinal tract. KGF may also be given to treat oral mucositis or as GVHD prophylaxis.

Ursodiol: A naturally occurring bile acid used to dissolve small gall stones and to increase bile flow in patients with primary biliary cirrhosis.

Section Updates:

Question Number Date of Change Add/Remove/Modify Description Reasoning (If applicable)
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Last modified: Oct 29, 2021

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