Optional for Non-U.S. Centers

The following questions refer to initial platelet recovery following the HCT for which this form is being completed. All dates should reflect no platelet transfusions administered for seven consecutive days. Report the date of the first of three consecutive laboratory values ≥ 20 × 109/L obtained on different days, as shown in the Reporting Platelet Recovery example below. Note that platelet recovery may take place well after the recipient has returned to the referring physician for care. It is essential that information and laboratory values be obtained from the referring physician.

Transfusions temporarily increase blood cell counts. When the data is later used for analysis, it is important to be able to distinguish between a recipient whose own body was creating the cells and a recipient who required transfusions to support the counts.

The following example illustrates the procedure to follow for reporting platelet recovery.

Reporting Platelet Recovery

Transfusion
Day 0 1 2 3 4 5 6 7 8 9 10
Platelet Count 10,000 35,000 30,000 25,000 10,000 15,000 19,000 23,000 25,000 40,000 50,000
Date 1/1/2008 1/2/2008 1/3/2008 1/4/2008 1/5/2008 1/6/2008 1/7/2008 1/8/2008 1/9/2008 1/10/2008 1/11/2008
1st of 3

Report 1/8/08 as date platelet count ≥ 20 × 109/L

Question 17: Was an initial platelet count ≥ 20 × 109/L achieved?

Indicate whether or not there was evidence of initial platelet recovery following this HCT.

Check only one response:

  • If “yes,” continue with question 18.
  • If “no,” continue with question 19.
  • Check “not applicable,” if the recipient’s platelets never dropped below 20 × 109/L at any time post-HCT and a platelet transfusion was never required. If the recipient’s platelet count drops below 20 × 109/L and/or the recipient received a platelet transfusion even once, do not use this option. This option is only applicable in the 100-day reporting period. Continue with question 19.
  • Check “previously reported” if this is the six-month or annual follow-up, and initial platelet recovery has already been reported on a previous form. Continue with question 19.

Question 18: Date platelet ≥ 20 × 109/L

Enter the first date of three consecutive laboratory values obtained on different days where the platelet count was ≥ 20 × 109/L. Ensure that no platelet transfusions were administered for seven days immediately preceding this date. Include day seven, as shown in the Reporting Platelet Recovery example above, when determining the recovery date.

If three laboratory values were not obtained on consecutive days, but a sequential rise of ≥ 20 × 109/L is demonstrated, follow the examples below when determining an estimated date.

Reporting Scenarios:

A. The recipient is being seen in the outpatient clinic and receives a platelet transfusion on January 1. The platelet count is 22 × 109/L on January 2, 24 × 109/L on January 3, and 28 × 109/L on January 4. The recipient does not come into the clinic for evaluation until one month later. The recipient has not received any more platelet transfusions and the platelet count is well above 20 × 109/L. Report January 8 (day seven post-platelet transfusion) for the date of platelet recovery.

B. The recipient is being seen in the outpatient clinic and receives a platelet transfusion on January 1. The platelet count is ≥ 20 × 109/L on January 2, January 3, and January 4. The recipient is then discharged back to their primary care physician. The transplant center receives a follow-up note from the primary care physician that states “recipient recovered their platelets in January of 2011.” Report an estimated date of recovery using the guidelines available in General Instructions, General Guidelines for Completing Forms.

For more information regarding reporting partial or unknown dates, see General Instructions, General Guidelines for Completing Forms.

Last modified: Apr 07, 2020

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