Welcome to the CIBMTR Forms Instruction Manual. The Table of Contents on the left side of the screen is for navigational purposes; if you are on a mobile device you may find the Table on Contents on the top of the page.

General Instructions provides useful general background information for successfully completing forms.

2804/2814: CRID Assignment and Indication provides explanatory text used to generate a CIBMTR Research ID (CRID) and report the indication.

Transplant Essential Data (TED) Manuals provides explanatory text for each question found on the TED forms.

Comprehensive Baseline & Follow-up Forms Manuals provides explanatory text for each question on the Baseline, Follow-up, IDMs, HLA, and Infusion forms.

Comprehensive Disease Specific Manuals provides explanatory text and additional information for disease indications requiring CIBMTR reporting.

Cellular Therapy Manuals provides explanatory text for completing pre-infusion, infusion, and post-infusion forms

Infection & Miscellaneous Manuals provides explanatory text for manuals such as the Hepatitis Serology, VOD / SOS, and Myelofibrosis CMS Study forms.

Appendices provide additional information beyond the scope of the other manuals.

Manual Updates:
Sections of the Forms Instruction Manual are frequently updated. In addition to documenting the changes within each manual section, the most recent updates to the manual can be found below. For additional information, select the manual section and review the updated text.

Date Manual Section Add/Remove/Modify Description
6/17/19 2400: Pre-TED Modify Added additional information (in red below) to the instructional text for question 40 to better define the related donor types listed on the form:
Indicate the relationship and match between the recipient and the donor. Only consider HLA-A, B, C, and DRB1 when determining the donor’s match / mismatched relationship to the recipient.
  • Syngeneic:
    • Includes: Monozygotic (identical) twins. Occurs when a single egg is fertilized to form one zygote, which then divides into two separate embryos.
    • Does not include: Other types of twins or HLA-identical siblings (see below).
  • HLA-identical sibling:
    • Includes: Non-monozygotic (dizygotic, fraternal, non-identical) twins. Occurs when two eggs are fertilized by two different sperm cells at the same time. This category also includes siblings who aren’t twins, but have identical HLA types. The patient and donor will be allele-level matched at HLA-A, B, C, and DRB-1.
    • Does not include: Half-siblings (report as “HLA matched other relatives” if their HLA is a match, or “mismatched relative” if it does not match).
  • HLA-matched other relative:
    • Includes: All blood-related relatives, other than siblings, who are HLA matched (e.g., parents, aunts, uncles, children, cousins, half-siblings). The patient and donor will be allele-level matched at HLA-A, B, C, and DRB1.
    • Does not include: Adoptive parents/children or stepparents/children who are HLA matched.
  • HLA-mismatched relative:
    • Includes: Siblings who are not HLA-identical and all other blood-related relatives who have at least one HLA mismatch (e.g., parents, aunts, uncles, children, cousins, half-siblings). This includes haploidentical donors. The patient and donor will be allele-level mismatched at one or more loci (HLA-A, B, C, or DRB1).
    • Does not include: Adoptive parents/children or stepparents/children.
5/14/2019 F4100 Cellular Therapy Essential Data Follow-up Remove Removed note box Survival status For scenarios where both HCT and CT forms will be submitted at the same time, there are duplicate questions across the F2100 and F4100. To reduce the reporting burden, duplicated questions on the Cellular Therapy forms are disabled. This includes Survival Status reported on F4100.
Last modified: 2019/06/17

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