The Research Sample Repository contains approximately 2.8 million sample aliquots from more than 57,000 first allogeneic related and unrelated transplant recipient/donor (or cord blood) pairs with complete, validated clinical outcome data from the CIBMTR Observational Database. The majority of the paired samples have complete high-resolution data available for HLA-A, B, C, DRB1/3/4/5, DQ and DP loci.
Sample Types
Samples in the Research Sample Repository are stored as:
- Whole blood
- Cryopreserved whole blood
- Plasma
- Blood spotted on filter paper
- Peripheral blood mononuclear cells (PBMC) viable and non-viable
- B-Lymphoblastoid cell lines (B-LCL) viable and non-viable
- Granulocytes
- Serum
- DNA
- Whole genome amplified DNA
Available sample types vary by sample source and year of collection. Sample sources include: adult and pediatric related/unrelated donors, cord blood and transplant recipients. Samples from recipients are drawn before the patient’s conditioning regimen begins. Prior to January 1, 2000, 100-day post-transplant samples were also drawn.
Inventory Summary
| Number of unrelated Donor/Recipient pairs: |
43,432 |
| Number of unrelated Single Cord
blood/Recipient pairs: | 3,106 |
| Number of unrelated Multi
Cord blood/Recipient pairs: |
1,753 |
| Number of unique unrelated Donor ID: |
75,883 |
| Number of unique unrelated Recipient ID: |
70,584 |
| Number of unique Cord ID: |
12,936 |
| Number of unique related Donor ID: |
10,837 |
| Number of unique related Recipient ID: |
11,275 |
| Number of related Donor/Recipient Pairs: |
9,513 |
View a detailed summary of available recipient and/or donor samples from first transplants, which includes information about the sample inventory by variable, including: age, gender, high-resolution typing, disease status, graft type, conditioning regimen, GVHD prophylaxis, and more: Repository Sample Inventory (PDF).
More information
For information about the availability of sample types or specific inventory queries, contact research-repos@nmdp.org.
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