The Research Sample Repository contains approximately 2.7 million sample aliquots from more than 49,000 first allogeneic related and unrelated transplant recipient/donor (or cord blood) pairs with complete, validated clinical outcome data from the CIBMTR Observational Database. The majority of the paired samples have complete high-resolution data available for HLA-A, B, C, DRB1/3/4/5, DQ and DP loci.

Sample Types

Samples in the Research Sample Repository are stored as:

• Whole blood
• Cryopreserved whole blood
• Plasma
• Blood spotted on filter paper
• Peripheral blood mononuclear cells (PBMC) viable and non-viable
• B-Lymphoblastoid cell lines (B-LCL) viable and non-viable
• Granulocytes
• Serum
• DNA
• Whole genome amplified DNA

Available sample types vary by sample source and year of collection. Sample sources include: adult and pediatric related/unrelated donors, cord blood and transplant recipients. Samples from recipients are drawn before the patient’s conditioning regimen begins. Prior to January 1, 2000, 100-day post-transplant samples were also drawn.

Inventory Summary

View a detailed summary of available recipient and/or donor samples from first transplants, which includes information about the sample inventory by variable, including: age, gender, high-resolution typing, disease status, graft type, conditioning regimen, GVHD prophylaxis, and more: Repository Sample Inventory (PDF).

More information

For information about the availability of sample types or specific inventory queries, contact research-repos@nmdp.org.

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