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The Research Sample Repository contains cell and serum samples collected from related and unrelated transplant donors, cord blood units and recipients.
The primary objective of the Research Sample Repository is to make these samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT).
These data may be used in research to:
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The Research Sample Repository includes cell and serum samples from allogeneic related and unrelated donors and recipients. The protocol also allows for submission of research samples from registered donors with rare tissue types. Complete eligibility requirements are outlined in the study protocol.
To be compliant with United States Federal Regulations for human research subject protection, U.S. transplant centers must obtain IRB-approved informed consent from recipients before submitting samples to the Research Sample Repository.
Although all NMDP/Be The Match centers participate in the Research Sample Repository protocol, only select NMDP/Be The Match centers currently submit related recipient and donor samples. In the future, additional NMDP/Be The Match centers may be invited to submit related recipient and donor samples.
If your center only performs related donor HCT and/or autologous HCT, you will not submit research samples, and therefore do not need to obtain IRB approval for your center for the Research Sample Repository protocol.
Upon obtaining center IRB approval, the CIBMTR Protocol Coordinator must receive a copy of the center's IRB approval letter, approved protocol and informed consent documents. These documents should be sent via email to:
Alexandra Erickson, Immunobiology Research ScientistRepositoryIRB@nmdp.orgTelephone: (763) 406-5851
CIBMTR tracks the IRB approval for the Research Sample Repository at each participating center. The center's IRB approval for this protocol must be current at all times. Failure to have current IRB approval may affect your center's ability to meet CPI requirements for sample submission.
The CIBMTR, through the NMDP/Be The Match IRB, has approved the following protocol and consent form templates. Your center must have IRB approval for the protocol and consent forms relevant to your center. The protocol must be submitted as written for center IRB approval.
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