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The Research Sample Repository contains cell and serum samples collected from related and unrelated transplant donors, cord blood units and recipients.
The primary objective of the Research Sample Repository is to make these samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT).
These data may be used in research to:
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The Research Sample Repository includes cell and serum samples from allogeneic related and unrelated donors and recipients. The protocol also allows for submission of research samples from registered donors with rare tissue types. Complete eligibility requirements are outlined in the study protocol.
To be compliant with United States Federal Regulations for human research subject protection, U.S. transplant centers must obtain IRB-approved informed consent from recipients before submitting samples to the Research Sample Repository.
Although all NMDP/Be The Match centers participate in the Research Sample Repository protocol, only select NMDP/Be The Match centers currently submit related recipient and donor samples. In the future, additional NMDP/Be The Match centers may be invited to submit related recipient and donor samples.
If your center only performs related donor HCT and/or autologous HCT, you will not submit research samples, and therefore do not need to obtain local IRB approval for the Research Sample Repository protocol.
Upon obtaining local IRB approval, the NMDP/Be The Match IRB Office must receive a copy of the local IRB’s approval letter, approved protocol and informed consent documents. These documents should be sent to:
Christina Jobe, Sr. Human Research Protection Program SpecialistNational Marrow Donor Program/Be The Match500 N. 5th St.
Minneapolis, MN 55401E-mail:
email@example.comTelephone: (763) 406-8164Fax: (763) 406-5899
The NMDP/Be The Match IRB Office tracks the IRB approval for the Research Sample Repository at each participating center. Your center will receive a renewal reminder approximately two months in advance of the local continuing review date. Local IRB approval for this protocol must be current at all times. Failure to have current local IRB approval may affect your center’s ability to meet CPI requirements for sample submission.
The CIBMTR, through the NMDP/Be The Match IRB, has approved the following protocol and consent forms. Your center must submit these documents to your local IRB for review and approval. CIBMTR and NMDP/Be The Match allow the consent forms to be formatted according to each site’s requirements, but requires the protocols to be submitted as written.
The donor consent form has been submitted for translation. In the meantime, U.S. federal regulations allow for the use of a Short Form when a fully translated consent form is not available. If you need the Short Form, please contact
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