Types of Data Available for Research or Request
The CIBMTR Observational Database contains hematopoietic cell transplantation (HCT) data for recipients and their donors. CIBMTR collaborates with centers from around the world to collect clinical data from:
- Nearly all allogeneic transplants performed in the U.S.
- Approximately 25% of allogeneic transplants performed outside of the U.S.
- Approximately 60% of autologous transplants performed in North and South America
Data available for research purposes
CIBMTR supports investigators in conducting HCT observational studies. Data available for this research includes:
Baseline recipient data
- Diagnosis – disease subclassification or histology, stage at transplant, cytogenetics, molecular markers, pre-HCT disease treatment
- Demographic – socioeconomic information, gender, age, race/ethnicity
- Transplant procedure – HLA typing, conditioning regimen, graft source, mobilization, T-cell depletion and other graft manipulation
- Clinical – coexisting diseases, pre-HCT infection, HCT history
Baseline donor data
- Demographics
- HLA typing
- Infection diease markers
- Pre-donation CBC and differential
- Pre-donation toxicities
- Filgrastim administration
Follow-up recipient data
Collected at 100 days, 6 months and annually after HCT:
- Transplant outcomes:
- survival
- neutrophil and platelet engraftment
- acute and chronic GVHD
- relapse
- GVHD prophylaxis
- Immune reconstitution
- Chimerism
- Infection
- Organ function
- Subsequent HCT or DCI
- New malignancy
- Cause of death
Follow-up donor data
Collected at 2 days, 1 week and weekly until donor reports full recovery, then at 1 month, 6 months and annually after donation:
- Donor outcomes – post-donation CBC and differential, post-donation toxicities, adverse events
- Product analysis – cell counts, viability, volume
Investigators are welcome to view the data collection forms and the Data Management Manual for more information on the collection of recipient and donor data.
